Correction: Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage.

Correction for 'Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage' by John Ivarsson , , 2024, , 7849-7864, https://doi.org/10.1039/D4FO01874E.

Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage.

As the first line of defense, the skin is equipped with various physiological mechanisms positioned to prevent incoming oxidative damage from numerous environmental insults. With persistent exposure to the environment, understanding ways to augment the skin defenses is paramount in protecting from premature aging. In this study, we investigated the ability of five dietary phenolic metabolites, typically found in the bloodstream after wild blueberry consumption, to successfully defend the skin from UV light exposure in a novel co-culture model of human skin explants and primary endothelial cells.

Combined exposure to UV and PM affect skin oxinflammatory responses and it is prevented by antioxidant mix topical application: Evidences from clinical study.

Background: Exposure to environmental stressors like particulate matter (PM) and ultraviolet radiation (UV) induces cutaneous oxidative stress and inflammation and leads to skin barrier dysfunction and premature aging. Metals like iron or copper are abundant in PM and are known to contribute to reactive oxygen species (ROS) production.

Aims: Although it has been suggested that topical antioxidants may be able to help in preventing and/or reducing outdoor skin damage, limited clinical evidence under real-life exposure conditions have been reported.