Background: Axicabtagene ciloleucel (axi-cel), a chimeric antigen receptor (CAR) T-cell therapy, has significantly improved clinical outcomes in adult patients with relapsed/refractory large B-cell lymphoma (LBCL). However, few studies have examined patient-reported outcomes (PROs) or neurocognitive performance in patients treated with axi-cel. Moreover, no longitudinal PRO study has reported on patients treated with axi-cel as standard of care in the United States, to our knowledge.
View Article and Find Full Text PDFHuanglongbing (HLB), also known as citrus greening disease, is a devastating disease of citrus. However, there is no known cure so far. Recently, under Section 24(c) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), a special local need label was approved that allows the trunk injection of antimicrobials such as oxytetracycline (OTC) for HLB management in Florida.
View Article and Find Full Text PDFBackground: As the number of programs aimed at preventing fragility fractures and mitigating the phenomenon of cascade fractures is increasing worldwide, so it is necessary to evaluate the effectiveness of such programs to seek their feasible implementation at regional and global levels.
Aims: This paper aims to provide an overview focusing on the incidence of secondary fractures after the implementation of any type of fracture liaison service (FLS). To this end, a scoping review was conducted focusing on the identification of clinical evidence reported in systematic reviews of the medical literature in this area.
Endometriosis is a debilitating disease affecting 190 million women worldwide and the greatest single contributor to infertility. The most broadly accepted etiology is that uterine endometrial cells retrogradely enter the peritoneum during menses, implant and form invasive lesions in a process analogous to cancer metastasis. However, over 90% of women suffer retrograde menstruation, but only 10% develop endometriosis, and debate continues as to whether the underlying defect is endometrial or peritoneal.
View Article and Find Full Text PDFAgricultural residues represent a valuable opportunity to develop circular bioeconomic systems centered on biomass. Characterizing this type of biomass can alleviate the pressure on current biomass sources (e.g.
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