Publications by authors named "J Horwath-Winter"
Purpose: Artificial intelligence (AI)-tools hold great potential to compensate for missing resources in health-care systems but often fail to be implemented in clinical routine. Intriguingly, no-code and low-code technologies allow clinicians to develop Artificial intelligence (AI)-tools without requiring in-depth programming knowledge. Clinician-driven projects allow to adequately identify and address real clinical needs and, therefore, hold superior potential for clinical implementation.
View Article and Find Full Text PDFApplication frequency - key indicator for the efficiency of severe dry eye disease treatment - evidence for the importance of molecular weight of hyaluronan in lubricating agents.
Acta Ophthalmol
August 2024
Article Synopsis
- The study investigates the effectiveness of high molecular weight hyaluronan (HA) eye drops in reducing the frequency of eye drop applications in patients with severe dry eye disease (DED).
- It compares patients using these high Mw HA drops (hylan A) with those using lower Mw HA drops over an 8-week period, measuring changes in drop frequency and overall eye health.
- Results showed that hylan A users significantly decreased their eye drop frequency by week 4 and maintained this improvement up to week 8, with noticeable benefits in their ocular health metrics.
Article Synopsis
- The study investigates dupilumab (Dupixent®)-associated ocular surface disease (DAOSD) in patients with moderate-to-severe atopic dermatitis (AD).
- It involved 20 AD patients and 10 healthy controls, examining their ocular health through detailed examinations and microbiome assessments before and after treatment with dupilumab.
- Results indicated that 6 patients developed DAOSD, with notable neutrophil activity and shifts in the ocular microbiome, highlighting a complex interaction between the medication and ocular health.
The word "elective" refers to medications and procedures undertaken by choice or with a lower grade of prioritization. Patients usually use elective medications or undergo elective procedures to treat pathologic conditions or for cosmetic enhancement, impacting their lifestyle positively and, thus, improving their quality of life. However, those interventions can affect the homeostasis of the tear film and ocular surface.
View Article and Find Full Text PDFArticle Synopsis
- This study examines how various methods define the center of a keratoconus cone and analyzes inconsistencies among these definitions across tomographic maps.
- Researchers reviewed corneal tomographic data from 162 eyes with keratoconus using five different location-determining methods and measured the distances between each method's results.
- Findings indicate that curvature-based methods show significant discrepancies compared to elevation and pachymetry-based methods, with larger deviations linked to less severe keratoconus and more peripheral cone positions.