Publications by authors named "J Hormazabal"
has emerged as a significant human pathogen, acquiring multiple antibiotic resistance genes, including carbapenemases. This study focuses on characterizing the plasmids harboring the and (Y) genes in two carbapenem-resistant isolates (UCO-553 and UCO-554) obtained in Chile during the COVID-19 pandemic. : Antibiotic susceptibility testing was conducted on UCO-553 and UCO-554.
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- This study examined the genetic makeup of Neisseria meningitidis strains from Chilean children using whole-genome sequencing (WGS) to assess potential vaccine effectiveness.* -
- Out of 42 strains analyzed, the most common types were MenB and MenW, with findings indicating varying levels of predicted vaccine coverage using tools like gMATS and MenDeVAR.* -
- The results revealed significant genetic variability among Chilean strains compared to those in other countries, which limits the ability to predict vaccine coverage accurately with existing methods.*
Article Synopsis
- A pregnant woman with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia required treatment with daptomycin and cefazolin after vancomycin failed.
- Family contact analysis found a similar MRSA strain in her mother, but no MRSA was found in their household cats.
- This case highlights the potential for MRSA to affect pregnant women and indicates that combined therapies may be necessary while also considering family members as potential carriers that may need treatment.
Since the SARS-CoV-2 outbreak in 2019, a diversity of viral genomic variants has emerged and spread globally due to increased transmissibility, pathogenicity, and immune evasion. By the first trimester of 2023 in Chile, as in most countries, BQ and XBB were the predominant circulating sub-lineages of Omicron. The molecular and antigenic characteristics of these variants have been mainly determined using non-authentic spike pseudoviruses, which is often described as a limitation.
View Article and Find Full Text PDFserovar Typhi (. Typhi), a human-restricted pathogen, invades the host through the gut to cause typhoid fever. Recent calculations of the typhoid fever burden estimated that more than 10 million new typhoid fever cases occur in low and middle-income countries, resulting in 65,400-187,700 deaths yearly.
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