Publications by authors named "J Horejsek"

Purpose: The echocardiography parameters may predict the maintenance of sinus rhythm after cardioversion of a supraventricular arrhythmia (SVA).

Materials And Methods: Patients in septic shock with onset of an SVA, normal to moderately reduced LV systolic function (EF_LV˃̳35%) and on a continuous noradrenaline of <1.0 μg/kg.

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Aims: A recently published trial has shown no differences in outcomes between patients with new-onset supraventricular arrhythmia (SVA) in septic shock treated with either propafenone or amiodarone. However, these outcome data have not been evaluated in relation to the presence or absence of a dilated left atrium (LA).

Methods And Results: Patients with SVA and a left ventricular ejection fraction ≥ 35% were randomized to receive intravenous propafenone (70 mg bolus followed by 400-840 mg/24 h) or amiodarone (300 mg bolus followed by 600-1800 mg/24 h).

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Article Synopsis
  • Acute supraventricular arrhythmias can worsen hemodynamic stability in patients with septic shock, and a study compared the effects of intravenous propafenone and amiodarone on arrhythmias in this population.
  • In a trial with 209 patients, those receiving propafenone had a quicker return to sinus rhythm (3.7 hours) compared to those on amiodarone (7.3 hours), although the overall 24-hour sinus rhythm rates were similar.
  • Propafenone led to fewer cases of arrhythmia recurrence than amiodarone, especially in patients without a dilated left atrium, indicating it may be a more effective option for short-term management.
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  • - The study aimed to assess how accurately the collapsibility of the internal jugular vein (IJV) can predict fluid responsiveness in patients who are breathing on their own after heart surgery.
  • - Conducted with 54 patients post-cardiac surgery, results showed that while those who responded to fluid therapy had lower IJV diameters at baseline, the overall ability of IJV collapsibility to predict fluid responsiveness was limited.
  • - The findings concluded that IJV collapsibility is not a reliable predictor for fluid responsiveness in these patients, with a sensitivity of 76.5% and a specificity of only 38.9%.
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  • End-expiratory occlusion (EEO) and end-inspiratory occlusion (EIO) tests were evaluated to see if they could accurately predict fluid responsiveness in patients after cardiac surgery.
  • The study involved 57 patients who underwent elective coronary artery bypass grafting, focusing on measurements like cardiac index (CI) and stroke volume before and after fluid expansion.
  • Results showed that neither EEO nor EIO could reliably predict fluid responsiveness, with a combined measure showing low sensitivity and specificity when assessing CI changes.
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