Publications by authors named "J Hordijk"
Article Synopsis
- * This study investigates the interaction between two subgroups of I-complex plasmids, IncK1 and IncK2, focusing on their RNAI structures, which differ by only five nucleotides and determine their compatibility.
- * Through experiments with minireplicons and targeted mutations, the research found that only specific nucleotide changes in the RNAI structure affect compatibility, highlighting the importance of these findings for predicting plasmid behavior in future research.
The gut microbiome of humans and animals acts as a reservoir of extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC). Dogs are known for having a high prevalence of ESBL-EC in their gut microbiota, although their ESBL-EC carrier status often shifts over time. We hypothesized that the gut microbiome composition of dogs is implicated in ESBL-EC colonization status.
View Article and Find Full Text PDFDiet is an important determinant of the human gut microbiome. Here, we analyzed fecal metagenomes of Dutch adults following omnivorous, pescatarian, vegan, and vegetarian diets. We compared the taxonomic composition of individuals from our study with publicly available gut metagenomes from westernized and non-westernized societies.
View Article and Find Full Text PDFObjectives: Plasmid-mediated colistin resistance can be transferred from animals to humans. We investigated the prevalence of carriage of -mediated colistin-resistant and (ColR-E/K) in veterinary healthcare workers and in the general population in the Netherlands.
Methods: Two cross-sectional population studies were performed: one among veterinary healthcare workers and one in the general population.