Publications by authors named "J Horakova"
Article Synopsis
- The study compares two methods for measuring serum neurofilament light chain (sNfL) levels in multiple sclerosis patients: the established SIMOA method and the newer VEUS method, which is more automated and user-friendly.
- The results revealed significant differences in sNfL levels measured by the two methods, with SIMOA yielding notably higher concentrations than VEUS, despite the lack of correlation between the two.
- The findings highlight the VEUS method’s tendency to underestimate sNfL levels, suggesting that caution is needed when interpreting results from different diagnostic systems.
Article Synopsis
- The study investigates how different sterilization methods and solvent systems affect the degradation of electrospun biodegradable nanofibers made from polyesters, particularly for medical uses like vascular bandaging.
- Findings show that the sterilization method, either ethylene oxide or gamma irradiation, significantly influences how the materials degrade, with distinct degradation patterns observed depending on the method used.
- The choice of solvent for preparing the polymer solution also plays a crucial role, with the most accelerated degradation occurring in PLCL fibers made from organic acids and sterilized through gamma irradiation.
Glaucoma is a significant cause of blindness worldwide, and its treatment remains challenging. The disease progressively leads to damage to the optic disc and thus loss of visual acuity and visual field. High intraocular pressure (IOP) is a common risk factor.
View Article and Find Full Text PDFThe ever-increasing demands of modern medicine drive the development of novel drug delivery materials. In particular, nanofibers are promising for such materials due to their favorable properties. However, most development is still carried out through laboratory techniques that do not allow extensive and reproducible characterization of materials, which slows medical research.
View Article and Find Full Text PDFUndesirable postoperative tissue adhesions remain among the most common complications after surgery. Apart from pharmacological antiadhesive agents, various physical barriers have been developed in order to prevent postoperative tissue adhesions. Nevertheless, many introduced materials suffer from shortcomings during application.
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