Publications by authors named "J Homan van der Heide"

Background: While treatment of posttraumatic stress disorder (PTSD) in refugees is generally effective, many refugees remain symptomatic after treatment. Coping styles could be relevant to PTSD treatment response and as such may be a potential focus of PTSD treatment.

Aims: The study aims to examine 1) if baseline coping styles are related to treatment response after EMDR therapy or stabilization, and 2) if coping styles change during these treatments.

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Background: Ageing is a complex multifactorial process, impacting all organs and tissues, with DNA damage accumulation serving as a common underlying cause. To decelerate ageing, various strategies have been applied to model organisms and evaluated for health and lifespan benefits. Dietary restriction (DR, also known as caloric restriction) is a well-established long-term intervention recognized for its universal anti-ageing effects.

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Introduction: Patients with complex forms of posttraumatic stress disorder (PTSD) may benefit from schema therapy. While a small number of studies point to the effectiveness of individual schema therapy in refugees with PTSD, no evidence on group schema therapy (GST) in refugees exists. To illustrate and advocate for the use of GST in refugee patients with treatment-resistant PTSD and comorbid personality pathology, a case report is presented.

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Background: The use of an antibacterial envelope is cost-effective for patients at high risk of developing cardiac implantable electronic device (CIED) infection. The identification of these high-risk patients may be facilitated using a clinical risk score. The aim of the current study is to evaluate the PADIT score for identifying high-risk patients in patients undergoing a CIED procedure in a tertiary academic center.

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Article Synopsis
  • Serous borderline tumors (SBT) are ovarian lesions generally associated with a good prognosis, but 10-15% can progress to low-grade serous cancer (LGSC), which is aggressive and resistant to standard chemotherapy.
  • The research uses a combination of spatial proteomics and transcriptomics to understand the transition from SBT to LGSC, identifying an intermediary stage with micropapillary features (SBT-MP) and increased MAPK signaling.
  • Key findings include the discovery of specific proteins and transcripts linked to tumor invasiveness, alongside a blueprint for future studies on tumorigenesis and potential new treatment approaches for ovarian cancer.
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