Publications by authors named "J Herre"
Intercellular cell adhesion molecule 1 (ICAM-1) is a cell surface glycoprotein with a vital role in the immune response to pathogens. The expression pattern of ICAM-1 is wide ranging, encompassing endothelial cells, epithelial cells, and neutrophils. Recent work has characterized the role of ICAM-1 in murine neutrophils, but the function of human neutrophil ICAM-1 is incompletely understood.
View Article and Find Full Text PDFA man in his 60s undergoing liver transplant assessment was referred to the respiratory team after a thoracic CT scan revealed diffuse tree-in-bud changes. He had a history of infertility, chronic pancreatitis and liver cirrhosis with portal hypertension. Broncho-alveolar lavage was positive for Genetic screening found two cystic fibrosis transmembrane conductance regulator variants: Phe508del and Arg117His-7T.
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- There are notable differences in the clinical profiles and outcomes of patients with de novo heart failure (HF) compared to those with worsening chronic heart failure (WHF), particularly regarding diuretic treatment effects.
- A study analyzed data from the TRANSFORM-HF trial to compare the effects of torsemide vs furosemide on hospitalized patients with either type of HF, assessing outcomes like mortality and hospitalizations over 12 months.
- Results showed that patients with de novo HF were generally younger, had better kidney function, lower natriuretic peptide levels, and lower mortality and rehospitalization rates compared to WHF patients, indicating a less severe condition and better treatment response.
Background: The subcutaneous implantable cardioverter-defibrillator (S-ICD) was developed to avoid complications related to transvenous implantable cardioverter-defibrillator (TV-ICD) leads. Device safety and efficacy were demonstrated previously with atypical clinical patients or limited follow-up.
Objectives: The S-ICD PAS (Subcutaneous Implantable Cardioverter-Defibrillator System Post Approval Study) is a real-world, multicenter, registry of U.
Background: Cardiovascular disease remains the leading cause of mortality in human immunodeficiency virus-infected (HIV-positive) patients. Ventricular assist device therapy is rarely offered to these patients and data on outcomes are sparse. We investigated outcomes following ventricular assist device implants for HIV-positive as compared to non-HIV-infected (HIV-negative) patients.
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