Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss.

Secreted extracellular matrix components which regulate craniofacial development could be reactivated and play roles in adult wound healing. We report a patient with a loss-of-function of the secreted matricellular protein SMOC2 (SPARC related modular calcium binding 2) presenting severe oligodontia, microdontia, tooth root deficiencies, alveolar bone hypoplasia, and a range of skeletal malformations. Turning to a mouse model, Smoc2-GFP reporter expression indicates SMOC2 dynamically marks a range of dental and bone progenitors.

Functionalization of PTFE Materials Using a Combination of Polydopamine and Platelet-Rich Fibrin.

Background: The diaphragm, which forms a physical barrier between the thoracic and the abdominal cavities, is also the major part of the respiratory system. Congenital diaphragmatic hernia (CDH) is a malformation of that partition muscle. Expanded polytetrafluoroethylene (e-PTFE), a synthetic nondegradable biomaterial, is currently used for the repair of diaphragm defects.

Technical Quality of Root Canal Filling in Preclinical Training at Strasbourg University Using Two Teaching Protocols.

Objectives:  The aim of this study was to compare two teaching protocols according to the technical quality of root canal therapy (RCT) and the procedural errors occurred in preclinical training.

Materials And Methods:  Two different groups of students were concerned. The first one (G1) performed a crown-down technique to shape the root canal systems and cold lateral condensation technique to fill them.

Effectiveness of Etching by Three Acids on the Morphological and Chemical Features of Dentin Tissue.

Aim: The purpose of this study was to evaluate the microscopic and chemical effects of phosphoric acid gel, phosphoric acid liquid, and polyacrylic acid application for 15 seconds (s) on coronal dentin.

Materials And Methods: Twelve extracted teeth were selected. Three etching acids were used to prepare the dentin surfaces.

Effect of etching the coronal dentin with the rubbing technique on the microtensile bond strength of a universal adhesive system.

Background: The adhesion of composite resins to the dentin substrate is influenced by the treatment of the smear layer. While etch-and-rinse systems require dentin to be conditioned with phosphoric acid, self-etching systems preserve the smear layer by incorporating it into the adhesive layer.

Objectives: The objective of this study was to evaluate the influence of etching with the rubbing technique on the microtensile bond strength (μTBS) of a universal adhesive to dentin.