Publications by authors named "J Heianna"

Utility values of responders and nonresponders are essential inputs in cost-effectiveness studies of radiation therapy for painful bone metastases but, to our knowledge, they have not been reported separately. We sought to determine the utility values of responders and nonresponders using data from a prospective observational study on bone metastases. The original prospective observational study was conducted at 26 centers in Japan.

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Pre-treatment depiction of the cervical arteries is important for better intra-arterial infusion therapy of malignant head and neck tumors. There have not been any studies on the image quality of ultra-high-resolution computed tomography (U-HRCT) for cervical CT angiography (CTA). The aim of this study is to evaluate the advantages of U-HRCT over conventional HRCT for cervical CTA; Methods: Forty-one patients underwent cervical CTA prior to selective intra-arterial infusion chemotherapy for malignant head and neck tumors.

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Arterial spin labeling (ASL) magnetic resonance angiography (MRA) (ASL-MRA) is a newly developed method that can visualize small arteries, particularly those running tortuously and inferiorly at slow flow rates. It provides excellent visualization of the external carotid artery system, with superior performance in visualizing the middle meningeal artery (MMA) compared to that of computed tomography angiography (CTA). Here, we report a case of maxillary sinus carcinoma in which ASL-MRA revealed an ipsilateral ophthalmic artery originating from the MMA that was not visualized on CTA.

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Article Synopsis
  • This study aimed to evaluate the real-world impact of radiotherapy for bone metastases on patients' quality of life (QOL) using data from 26 centers in Japan.
  • Out of 333 patients receiving treatment, 232 were included, and their QOL was assessed at enrollment and followed up at two and six months using standardized questionnaires.
  • Results showed significant improvements in several QOL areas, especially pain and insomnia, indicating that radiotherapy can positively affect some aspects of patient well-being in practice.
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Article Synopsis
  • This study assessed the characteristics, treatments, and outcomes of patients receiving radiotherapy for bone metastases across 26 hospitals in Japan from December 2020 to March 2021.* -
  • Out of 232 patients enrolled, findings showed that 52% experienced pain relief within two months, with a notable overall survival rate of 70.2% at six months.* -
  • Key observations included that 59% of patients had spinal metastases, the biologically effective dose (BED) of radiation varied widely, and the incidence of severe adverse events was low, with no significant relationship between BED and pain relief.*
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