Publications by authors named "J Hata"
Introduction: Nivolumab can cause various immune-related adverse events; it rarely induces Vogt-Koyanagi-Harada-disease-like uveitis. Vogt-Koyanagi-Harada-disease is reported to be closely associated with human leukocyte antigen-DR4.
Case Presentation: A 68-year-old man with metastatic renal cancer underwent nephrectomy.
Background & Aims: In addition to their adhesive properties, cell adhesion molecules such as claudins (CLDNs) exhibit signaling ability to organize diverse cellular events. Although the CLDN-adhesion signaling stimulates or inhibits cancer progression, the underlying mechanism remains poorly established. Here, we verified whether and how CLDN10 promotes intracellular signals and malignant phenotypes in clear cell renal cell carcinoma (ccRCC).
View Article and Find Full Text PDFGut microbiota plays a crucial role in the development and progression of prostate cancer, with previous studies indicating that certain bacterial taxa are more abundant in castration-resistant prostate cancer (CRPC) compared to hormone-sensitive prostate cancer (HSPC). Notably, the composition of gut microbiota can vary significantly by geographic region, and Japanese individuals have a distinct microbial profile. However, research exploring these differences within Japanese populations remains limited.
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- White adipose tissue (WAT) in mice can undergo a transformation known as "browning" when exposed to cold, resulting in the emergence of brown and beige adipocytes, which have distinct characteristics like dense mitochondria and multilocular lipid droplets.
- Research aimed to analyze the changes in diffusion parameters (T2* values and anisotropy) in brown adipose tissue (BAT), inguinal WAT (iWAT), and epididymal WAT (epiWAT) after cold exposure compared to normal conditions.
- The study revealed that T2* values in the control group’s epiWAT were significantly higher than in BAT and iWAT from the cold-exposed group, while specific eigenvalues showed
Studies have shown that tele-critical care (TCC) improves outcomes in intensive care unit (ICU) settings with low baseline performance. Evidence also suggests that TCC outcomes may be modified by heterogenous baseline severity of illness. We examined the association of admission Acute Physiology and Chronic Health Evaluation IV (APACHE IV) score quartiles (APQ1-APQ4) and TCC exposure with 30-day mortality.
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