Publications by authors named "J Hassanshahi"
Background And Purpose: Neuropathy is one of the common complications of diabetes mellitus. This study aimed to determine the analgesic and antiapoptotic effects of the aqueous extract of L. (Ach) in rats with experimental painful diabetic neuropathy by behavioral and molecular procedures.
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- * Mice were divided into six groups and received different treatments, including varying doses of Mor and PX, with pain response measured through a tail-flick test and dependence assessed using naloxone injections.
- * Results showed that PX reduced both the development of Mor tolerance and withdrawal symptoms in dependent mice, while also correcting certain biochemical abnormalities caused by Mor.
Background: Cisplatin, an anti-cancer chemotherapy drug, has nephrotoxic effects. Jalas (TCJ) has antioxidant effects due to its main components.
Objectives: In the current research, we assessed the impact of TCJ extract and its main compound on cisplatin-induced nephrotoxicity in mice.
Objective: Breast cancer causes death in women. Thymus Caramanicus Jalas (TCJ) as a polyphenolic plant has an antiproliferative effect. Accordingly, this investigation studied the TCJ extract anti-tumor effects in a breast cancer model.
View Article and Find Full Text PDFChronic opioid abuse can impair the hippocampal region of the brain. This study evaluates the neuroprotective effect of Achillea millefolium (Ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the CA1 region of the rat hippocampus. Thirty‑two male Wistar rat rats were classified into four treatment groups (n=8).
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