Publications by authors named "J Haring"
Article Synopsis
- - The TENSION trial evaluated the long-term safety and effectiveness of endovascular thrombectomy for patients with ischemic stroke and large infarcts, demonstrating favorable outcomes at 90 days, with a follow-up extending to 12 months.
- - Conducted across various hospitals in Europe and Canada, the trial involved patients aged 18 and older with acute ischemic strokes caused by large vessel occlusions, comparing results between those receiving thrombectomy plus medical care versus medical care alone.
- - Out of 253 enrolled patients, results indicated significant insights into functional outcomes, quality of life, and mental health aspects like anxiety and depression, although the trial concluded early due to promising efficacy in the treatment group.
Severe diaphragmatic myoclonus treated with unconventional therapy: A case report.
Respir Med Case Rep
June 2024
Article Synopsis
- - Diaphragmatic myoclonus is a rare condition involving involuntary contractions of the diaphragm and can have serious implications for those affected.
- - A case study is presented of a 61-year-old patient whose condition was linked to a bleeding cavernoma in the Guillan-Mollaret triangle, highlighting the specific challenges faced in treatment.
- - The patient successfully received botulinum toxin injections into the abdominal muscle after oral treatments failed, emphasizing the need for accurate diagnosis and effective interventions for severe cases of this condition.
Vascular dementia (VaD) is a white matter ischemic disease and the second-leading cause of dementia, with no direct therapy. Within the lesion site, cell-cell interactions dictate the trajectory towards disease progression or repair. To elucidate the underlying intercellular signaling pathways, a VaD mouse model was developed for transcriptomic and functional studies.
View Article and Find Full Text PDF: Basilar artery occlusion (BAO) is a serious disease with a poor prognosis if left untreated. Endovascular therapy (EVT) is the most effective treatment that is able to reduce mortality and disability. Treatment results are influenced by a wide range of factors that have not been clearly identified.
View Article and Find Full Text PDFBackground: Recent evidence suggests a beneficial effect of endovascular thrombectomy in acute ischaemic stroke with large infarct; however, previous trials have relied on multimodal brain imaging, whereas non-contrast CT is mostly used in clinical practice.
Methods: In a prospective multicentre, open-label, randomised trial, patients with acute ischaemic stroke due to large vessel occlusion in the anterior circulation and a large established infarct indicated by an Alberta Stroke Program Early Computed Tomographic Score (ASPECTS) of 3-5 were randomly assigned using a central, web-based system (using a 1:1 ratio) to receive either endovascular thrombectomy with medical treatment or medical treatment (ie, standard of care) alone up to 12 h from stroke onset. The study was conducted in 40 hospitals in Europe and one site in Canada.