Publications by authors named "J Hargrave"
Background: Amidst the COVID-19 pandemic, telemedicine emerged as an important option that supports and facilitates clinical practice, however, its usefulness in emergency settings that treat patients with cancer is unclear.
Objective: To evaluate patient perception of physician empathy in an emergency oncology setting, comparing video interaction to an in-person with personal protective equipment (PPE) approach.
Methods: In this single-center, prospective, cross-sectional, survey-based randomized controlled trial, patients were randomized 1:1 for the concluding conversation done in-person which included either interacting with physicians wearing PPE or video interaction with physicians without PPE (virtual).
Article Synopsis
- The BeSPoKE technique is a surgical method used to enlarge the aortic outflow tract in adults with complex heart issues, specifically those facing aortic stenosis and prosthesis-patient mismatch.
- A study involving 25 adults showed significant improvement in aortic valve gradients post-surgery, with a median size increase of the prosthesis and no reports of operative mortality.
- Postoperative complications included atrial fibrillation and heart block, but overall survival at two years was high at 92%, indicating that this technique is a safe and effective option for patients with small left ventricular outflow tracts.
Cystic Fibrosis (CF) results from the loss of function of the cystic fibrosis transmembrane conductance regulator (CFTR), an ion channel of key importance in the airway epithelia. CFTR helps control optimal hydration of the airways, a crucial requirement for healthy lungs. CFTR modulators have recently been approved as an effective treatment option for many genetic variants of CF.
View Article and Find Full Text PDFIntroduction: Fibrosing mediastinitis (FM) is a rare disease characterized by abnormal proliferation of fibrous tissue, causing compression and narrowing of the airway, blood vessels, and other mediastinal structures, including the pulmonary veins. Catheter-based interventions are available as palliative strategies. Due to the complex nature of the disease and the profound respiratory and hemodynamic sequelae that may ensue, anesthetic management requires meticulous interdisciplinary planning.
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- A study was conducted to evaluate the effects of combining liposomal bupivacaine with plain bupivacaine on pain management after minimally invasive thoracic surgery, hypothesizing it would provide better pain relief than bupivacaine alone.
- The research involved 189 patients and measured overall benefit of analgesia scores (OBAS), respiratory function, and opioid usage over the first three postoperative days.
- Results showed no significant difference in pain relief, respiratory mechanics, or opioid consumption between the two groups, indicating that liposomal bupivacaine did not offer advantages over standard bupivacaine.