Publications by authors named "J Hankin"

Background: Telehealth use rapidly increased during the COVID-19 pandemic, including for contraceptive care (e.g., counseling and method provision).

View Article and Find Full Text PDF

This study aims to evaluate whether incorporating gender differences in portion sizes as part of quantifying a food frequency questionnaire influences the association of total energy intake with mortality. The analysis included 156,434 participants (70,142 men and 86,292 women) in the Multiethnic Cohort Study, aged 45-75 years at baseline. A total of 49,728 deaths were identified during an average follow-up of 18.

View Article and Find Full Text PDF

Ion mobility measurements of product ions were used to characterize the collisional cross section (CCS) of various complex lipid [M-H] ions using traveling wave ion mobility mass spectrometry (TWIMS). TWIMS analysis of various product ions derived after collisional activation of mono- and dihydroxy arachidonate metabolites was found to be more complex than the analysis of intact molecular ions and provided some insight into molecular mechanisms involved in product ion formation. The CCS observed for the molecular ion [M-H] and certain product ions were consistent with a folded ion structure, the latter predicted by the proposed mechanisms of product ion formation.

View Article and Find Full Text PDF
Article Synopsis
  • Concerted tandem and traveling wave ion mobility mass spectrometry (CTS analysis) creates a detailed four-dimensional dataset that includes key characteristics like ion mass and abundance.
  • This innovative nontargeted lipidomics method was applied to analyze phospholipids in human serum using both positive and negative ion modes.
  • The study found that combining product ion mobility with unique collisional cross-section values significantly enhances the ability to identify lipids within complex biological samples.
View Article and Find Full Text PDF

A novel method for lipid analysis called CTS (collisional activation and traveling wave mass spectrometry), involving tandem mass spectrometry of all precursor ions with ion mobility determinations of all product ions, was applied to a sample of human serum. The resulting four-dimensional data set (precursor ion, product ion, ion mobility value, and intensity) was found to be useful for characterization of lipids as classes as well as for identification of specific species. Utilization of ion mobility measurements of the product ions is a novel approach for lipid analysis.

View Article and Find Full Text PDF