Publications by authors named "J Hahn-Pedersen"
Objective: This systematic literature review (SLR) aimed to investigate the role of neuroinflammation in AD and explore the association of neuroinflammation with AD disease progression.
Background: Several mediators of neuroinflammation can serve as therapeutic targets for Alzheimer's disease (AD) and as prognostic biomarkers.
Design/methods: A SLR was conducted in 2023 using MEDLINE®, Embase®, and PsycInfo® databases to identify English-language articles from 2012 on AD including mild cognitive impairment (MCI).
Background: Social media data provide a valuable opportunity to explore the effects that Alzheimer disease (AD) has on care partners, including the aspects of providing care that have the greatest impacts on their lives and well-being and their priorities for their loved ones' treatment.
Objective: The objective of this social media review was to gain insight into the impact of caring for someone with AD, focusing particularly on impacts on psychological and emotional well-being, social functioning, daily life and ability to work, health-related quality of life, social functioning, and relationships.
Methods: We reviewed social media posts from 4 sources-YouTube (Google), Alzheimer's Association, Alzheimer Society of Canada, and Dementia UK-to gain insights into the impact of AD on care partners.
Article Synopsis
- The text talks about new treatments for Alzheimer's disease and how effective they really are over time.
- It explains that these treatments may slow down the disease but most evidence is only available for a short period, making it hard to understand their real benefits.
- Researchers created a model to predict how these treatments could extend the time someone could manage their symptoms, showing promising results.
Background: Understanding the relationship among changes in Clinical Dementia Rating (CDR), patient outcomes, and probability of progression is crucial for evaluating the long-term benefits of disease-modifying treatments. We examined associations among changes in Alzheimer's disease (AD) stages and outcomes that are important to patients and their care partners including activities of daily living (ADLs), geriatric depression, neuropsychiatric features, cognitive impairment, and the probabilities of being transitioned to a long-term care facility (i.e.
View Article and Find Full Text PDF