Publications by authors named "J Hager"
Loss of Sult1a1 reduces body weight and increases browning of white adipose tissue.
Front Endocrinol (Lausanne)
December 2024
Background And Objective: Overweight and obesity affects millions of individuals worldwide and consequently represents a major public health concern. Individuals living with overweight and obesity have difficulty maintaining a low body weight due to known physiological mechanisms which prevent further weight loss and drive weight regain. In contrast, mechanisms which promote low body weight maintenance receive less attention and are largely unknown.
View Article and Find Full Text PDFCancers are driven by alterations in diverse genes, creating dependencies that can be therapeutically targeted. However, many genetic dependencies have proven inconsistent across tumors. Here we describe SCHEMATIC, a strategy to identify a core network of highly penetrant, actionable genetic interactions.
View Article and Find Full Text PDFArticle Synopsis
- Microbially induced corrosion (MIC) affects environmental issues, such as interactions with radioactive waste and the role of microbes in environmental cleanup.
- A step-by-step protocol for preparing bacterial biofilms for analysis using time-of-flight secondary ion mass spectrometry (ToF-SIMS) is discussed, comparing three techniques: no desalination, centrifugal spinning (CS), and water submersion (WS).
- Results show that CS significantly reduces media peaks and enhances biological signals, revealing chemical changes in glass exposed to a specific bacterial biofilm over three months, indicating MIC effects.
Background: The aim of this retrospective observational study was to investigate the geographical or sex differences in patients with synchronous colorectal liver metastases (sCRLM) in terms of assessment by a multidisciplinary team conference (MDT), curative treatment, and overall survival.
Method: All sCRLM patients in the South-East Health Care Region of Sweden from 2009 to 2015 were included (n = 615). Data were derived from the Swedish Colorectal Cancer Registry, Swedish Registry of Liver and Bile Surgery and medical records.