Publications by authors named "J Hagendoorn"
Objective: To compare nationwide outcomes of robotic liver resection (RLR) with laparoscopic liver resection (LLR).
Background: Minimally invasive liver resection is increasingly performed using the robotic approach as this could help overcome inherent technical limitations of laparoscopy. It is unknown if this translates to improved patient outcomes.
The robotic platform enables surgeons to operate with a similar level of freedom and control as in open surgery, while still providing the patient with the benefits of a minimally invasive approach. More centres continue to adopt robotic liver surgery however standardized training materials and consensus on the surgical technique are currently lacking. The availability of a standardized surgical protocol could benefit the further dissemination of the robotic approach while promoting safe and effective operating techniques.
View Article and Find Full Text PDFPurpose: To describe the outcome of radiation lobectomy (RL) after double vein embolization (portal vein embolization + hepatic vein embolization) for patients with insufficient future liver remnant growth.
Materials And Methods: All patients with insufficient FLR function (as determined by hepatobiliary scintigraphy (HIDA); < 2.7%/min/m) after double vein embolization who underwent RL between 2020 and 2023 were selected.
Article Synopsis
- The study investigates how liver metastases contribute to the spread of colon cancer to the lungs, focusing on the role of VEGF-C.
- Researchers created organoids that overexpress VEGF-C and reimplanted them into mice, finding that this led to increased lymphatic vessel growth and lung metastasis.
- The findings suggest that targeting the VEGF-C and NOTCH pathways could potentially hinder the progression of colorectal cancer by limiting metastasis.
Background: Failure to rescue (FTR) is defined as the inability to prevent death after the development of a complication. FTR is a parameter in evaluating multidisciplinary postoperative complication management. The aim of this study was to evaluate FTR rates after major liver resection for perihilar cholangiocarcinoma (pCCA) and analyze factors associated with FTR.
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