Publications by authors named "J H de Wilt"
Article Synopsis
- There is evidence suggesting that using stents or decompressing stomas before surgery for left-sided obstructive colon cancer (LSOCC) is safer than emergency surgery, particularly for patients aged 70 and older.
- A study analyzing data from 2012 to 2020 showed a decrease in emergency resections, from 79.7% to 54.7%, with an increase in safer approaches like resection after stent or stoma.
- Despite a national trend towards safer surgical methods, some hospitals still performed over 75% emergency resections, leading to higher mortality rates, emphasizing the need to follow updated guidelines for elderly patients.
Reply - Letter to the editor entitled "Letter to editor regarding Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis".
Evertine Wesselink Hendriek C Boshuizen Anne-Sophie van Lanen Dieuwertje E Kok Jeroen W G Derksen Johannes H W de Wilt
Clin Nutr
November 2024
Article Synopsis
- Patients with colorectal cancer and liver-only metastases showed improved outcomes when treated with FOLFOXIRI and bevacizumab compared to FOLFIRI and bevacizumab or with panitumumab, especially regarding progression-free survival and resection rates.
- The CAIRO5 trial involved 530 patients with initially unresectable liver metastases from colorectal cancer, evaluated across numerous centers in the Netherlands and Belgium, focusing on different treatment combinations based on tumor genetics.
- While more effective responses were observed with certain treatments, there was an increase in toxic side effects, particularly in specific genetic tumor variants like RAS/BRAFV600E.
Reply - Letter to the editor entitled "Letter to editor - Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis".
Evertine Wesselink Hendriek C Boshuizen Anne-Sophie van Lanen Dieuwertje E Kok Jeroen W G Derksen Johannes H W de Wilt
Clin Nutr
December 2024
Light-based patterning of synthetic and biological hydrogels enables precise spatial and temporal control over the formation of chemical bonds. However, photoinitiators are typically used to generate free radicals, which are detrimental to human cells. Here, we report a photoinitiator- and radical-free method based on -nitrobenzyl alcohol (NBA) photolysis, which gives rise to highly reactive nitroso and benzaldehyde groups.
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