Peach ( ) TAC1 protein interaction with a LIGHT HARVESTING CHLOROPHYLL A/B BINDING (LHCB) homolog and transcriptomic analyses reveal connections to photosynthesis.

Plants receive and interpret external light, gravity, and temperature cues to both set and change the angles of their lateral organs for optimal growth and development. In recent years, the roles of the IGT/LAZY protein family in integrating light and gravity cues have become increasingly apparent. Here we investigated protein-protein interactions for peach ( ) TAC1 (PpeTAC1).

Combined effects of cannabidiol and Δ9-tetrahydrocannabinol alleviate migraine-like symptoms in mice.

Background: The therapeutic use of cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) to treat migraine has been understudied. Using three mouse models, we examined the impact of CBD and THC on migraine-relevant behaviors triggered by: 1) calcitonin gene-related peptide (CGRP), 2) sodium nitroprusside (SNP), and 3) cortical spreading depolarization (CSD).

Methods: Both male and female CD1 mice were treated with CBD (100 mg/kg) or THC (1 mg/kg) alone or in combinations of CBD (1, 30 or 100 mg/kg) and THC (1 mg/kg) prior to injection of CGRP or SNP.

Limited research investigating the value of MRI in predicting future cognitive morbidity in survivors of paediatric brain tumours: A systematic-review and call to action for clinical neuroimaging researchers.

Survivors of pediatric brain tumours are at a high risk of cognitive morbidity. Reliable individual-level predictions regarding the likelihood, degree, and affected domains of cognitive impairment would be clinically beneficial. While established risk factors exist, quantitative MRI analysis may enhance predictive value, above and beyond current clinical risk models.

Catechol redox maintenance in mussel adhesion.

Catechol-functionalized proteins in mussel holdfasts are essential for underwater adhesion and cohesion and have inspired countless synthetic polymeric materials and devices. However, as catechols are prone to oxidation, long-term performance and stability of these inventions awaits effective antioxidation strategies. In mussels, catechol-mediated interactions are stabilized by 'built-in' homeostatic redox reservoirs that restore catechols oxidized to quinones.

The Calicophoron daubneyi genome provides new insight into mechanisms of feeding, eggshell synthesis and parasite-microbe interactions.

Background: The rumen fluke, Calicophoron daubneyi, is the major paramphistome species infecting ruminants within Europe. Adult flukes reside within the rumen where they are in direct contact with a unique collection of microorganisms. Here, we report a 1.