Publications by authors named "J H Waddell"
The cerebellum, a key target of ethanol's toxic effects, is associated with ataxia following alcohol consumption. However, the impact of ethanol on Purkinje cell (PC) mitochondria remains unclear. To investigate how ethanol administration affects mitochondrial dynamics in cerebellar Purkinje cells, we employed a transgenic mouse model expressing mitochondria-targeted yellow fluorescent protein in Purkinje cells (PC-mito-eYFP).
View Article and Find Full Text PDF3D-printed suction clamps for tensile testing of brain tissue.
J Mech Behav Biomed Mater
December 2024
Article Synopsis
- The study presents a new method for mounting ultra-soft biological tissues using 3D-printed suction clamps, which reduces handling time and skill requirements compared to traditional methods.
- A total of 112 deer brain samples were tested, and 89 tests (85%) were successful, with slippage being the main failure issue, particularly in the medulla oblongata.
- The findings suggest that suction clamps improve efficiency in sample preparation and testing, while the success of testing varies by brain region.
Objective: Personalized normative feedback interventions show efficacy in reducing health risk behaviors (e.g., alcohol use, sexual aggression).
View Article and Find Full Text PDFPurpose: This study aimed to systematically review the literature to identify the incidence of avascular necrosis (AVN) following hip intra-articular corticosteroid injections (IACSIs) as well as to elucidate risk factors that may predispose patients to AVN following IACSI.
Methods: The MEDLINE, Embase, PubMed, and Web of Science databases were systematically searched through inception to July 21, 2024, in accordance with the PRISMA statement with data extracted for descriptive analysis. The inclusion criteria were hip IACSI and AVN of the femoral head.
Simultaneous alcohol and cannabis (SAM) use and alcohol mixed with energy drinks (AmED) days are associated with heavier drinking and negative consequences compared to alcohol-only days. However, it remains unclear if SAM and AmED days differ from one another in terms of consumption and negative consequences. It also remains unclear how often days characterized by both SAM + AmED occur and if these days are associated with incremental risk for heavier drinking and negative consequences.
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