A co-registration method to validate optical coherence tomography in the breast surgical cavity.

Breast-conserving surgery accompanied by adjuvant radiotherapy is the standard of care for patients with early-stage breast cancer. However, re-excision is reported in 20-30 % of cases, largely because of close or involved tumor margins in the specimen. Several intraoperative tumor margin assessment techniques have been proposed to overcome this issue, however, none have been widely adopted.

I love you no matter what: Negative relationship quality and daily encounters in the parent-child tie and their implications for daily mood across the lifespan.

Parent-child relationship quality has critical implications for parental emotional well-being across the lifespan. The present study assessed how relationship quality is related to daily encounters between parents and children, how those encounters are linked with parents' mood, and how these associations vary by age. Participants (N = 129, ages 33-91) reported baseline relationship quality with a total of 337 children (ages 1-69).

Towards a molecular picture of the archaeal cell surface.

Archaea produce various protein filaments with specialised functions. While some archaea produce only one type of filament, the archaeal model species Sulfolobus acidocaldarius generates four. These include rotary swimming propellers analogous to bacterial flagella (archaella), pili for twitching motility (Aap), adhesive fibres (threads), and filaments facilitating homologous recombination upon UV stress (UV pili).