Publications by authors named "J H Nicholas Ngiam"

Article Synopsis
  • Surgical weight loss (SWL) has been shown to improve heart function as measured by specific imaging techniques, but its effects compared to non-surgical methods in overweight Asian individuals were previously unstudied.
  • A study involved 66 patients who completed a 16-week lifestyle intervention program and revealed significant weight loss, but only a non-significant improvement in heart strain metrics.
  • In contrast, participants who underwent bariatric surgery exhibited notable improvements in heart function, confirming that surgical weight loss is a strong independent factor for enhancing heart strain parameters.
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Introduction: Tuberculous meningitis (TBM) can be difficult to diagnose. Elevated cerebrospinal fluid (CSF) adenosine deaminase (ADA) is often seen in TBM, but its reliability has been questioned. A previous meta-analysis in 2017 had demonstrated the diagnostic utility of CSF ADA in TBM versus non-TBM.

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The 'rule-of-6' prediction tool was shown to be able to identify COVID-19 patients at risk of adverse outcomes. During the pandemic, we frequently observed hyponatremia at presentation. We sought to evaluate if adding hyponatremia at presentation could improve the 'rule-of-6' prediction tool.

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Introduction: Early in the coronavirus disease 2019 (COVID-19) pandemic, a low incidence of cardiovascular complications was reported in Singapore. Little was known about the trend of cardiovascular complications as the pandemic progressed. In this study, we examined the evolving trends in electrocardiographic and cardiovascular manifestations in patients hospitalised with COVID-19.

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