Publications by authors named "J H Laake"
Objectives: Randomized clinical trials informing clinical practice (e.g., like large, pragmatic, and late-phase trials) should ideally mostly use harmonized outcomes that are important to patients, family members, clinicians, and researchers.
View Article and Find Full Text PDFLong-term mortality and health-related quality of life with lower versus higher oxygenation targets in intensive care unit patients with COVID-19 and severe hypoxaemia.
Intensive Care Med
October 2024
Article Synopsis
- - The study compared one-year outcomes of lower (8 kPa) and higher (12 kPa) oxygenation targets in ICU patients with COVID-19 and severe hypoxaemia, involving 726 randomly assigned patients.
- - Findings showed that 33.6% of patients in the lower-oxygenation group died, compared to 39.1% in the higher-oxygenation group, suggesting a potential benefit of the lower target, though results were not statistically significant (p = 0.11).
- - Health-related quality of life assessments indicated no significant differences between the two groups, with the lower-oxygenation group having a median EQ-VAS score of 50 vs 40 for the higher group (p
Purpose: To identify key components and variations in family-centered care practices.
Methods: A cross-sectional study, conducted across ESICM members. Participating ICUs completed a questionnaire covering general ICU characteristics, visitation policies, team-family interactions, and end-of-life decision-making.
Article Synopsis
- This clinical practice guideline from the European Society of Intensive Care Medicine focuses on the choice of resuscitation fluids for critically ill adult patients, with two more parts planned to address fluid volume and removal.
- An international panel of experts used the GRADE methodology to assess the evidence and guide their recommendations.
- The guideline offers conditional recommendations favoring crystalloids over albumin in various patient scenarios, while also addressing specific cases with varying levels of evidence certainty, such as traumatic brain injury and cirrhosis.
Purpose: Intensive care unit (ICU) survivors can experience wide-ranging and long-lasting symptoms after hospital discharge. Cognitive impairment has received increased attention in relation to the COVID-19 pandemic and can affect patients' long-term quality of life. This study aimed to investigate the prevalence of cognitive impairment using an objective neurocognitive test 6 and 12 months following ICU admission and possible predictive factors for scoring below the defined cut-off.
View Article and Find Full Text PDF