Detection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024.

We isolated three genotypes of highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.

Comprehensive Transcriptomic Analysis Reveals Cell-Type-Specific Roles of Human Odorant Receptors in Glioblastoma and the Tumor Microenvironment.

Odorant receptors (ORs), which constitute approximately 50% of all human G protein-coupled receptors, are increasingly recognized for their diverse roles beyond odor perception, including functions in various pathological conditions like brain diseases and cancers. However, the roles of ORs in glioblastoma (GBM), the most aggressive primary brain tumor with a median survival of only 15 months, remain largely unexplored. Here, we performed an integrated transcriptomic analysis combining The Cancer Genome Atlas RNA-seq and single-cell RNA sequencing data from GBM patients to uncover cell-type-specific roles of ORs within the tumor and its microenvironment.

Poststroke Ipsilesional Motor Performance: Microstructural Biomarkers and Their Associations With Executive Function.

Background: Unilateral hemispheric stroke can impair the ipsilesional motor performance, which is crucial for attaining optimal functional outcomes poststroke. However, the specific brain structures contributing to ipsilesional motor performance impairment remain unclear.

Objective: To explore the link between ipsilesional motor performance and the microstructural integrity of relevant neural pathways.

System Dynamics Modeling of Scale Formation in Membrane Distillation Systems for Seawater and RO Brine Treatment.

To overcome the limitations of traditional Reverse Osmosis (RO) desalination, Membrane Distillation (MD) has gained attention as an effective solution for improving the treatment of seawater and RO brine. Despite its potential, the formation of inorganic scales, particularly calcium sulfate (CaSO), continues to pose a major challenge. This research aims to explore the scaling mechanisms in MD systems through a combination of experimental analysis and dynamic modeling.