Safety and efficacy of an inactivated tetravalent water-in-oil emulsion vaccine against the peritonitis syndrome.

The purpose of the study was to prepare a safe vaccine that provides broad protection against the peritonitis syndrome. Two formaldehyde inactivated water-in-oil emulsion vaccines were made: one vaccine containing genotypes A (O1:H7), B (O78:H4), C (O2:H1) and D (O11:H12) (vaccine A-D), the other one only genotype A (vaccine A). genotypes originated from hens with EPS.

PatchProt: hydrophobic patch prediction using protein foundation models.

Motivation: Hydrophobic patches on protein surfaces play important functional roles in protein-protein and protein-ligand interactions. Large hydrophobic surfaces are also involved in the progression of aggregation diseases. Predicting exposed hydrophobic patches from a protein sequence has shown to be a difficult task.

Exposure, infection and disease with the tick-borne pathogen Borrelia miyamotoi in the Netherlands and Sweden, 2007-2019.

The impact of the emerging tick-borne pathogen Borrelia miyamotoi is not fully understood. We utilised a protein array to investigate B. miyamotoi seroreactivity in various human populations in the Netherlands and Sweden.

Online self-evaluation of fMRI-based neurofeedback performance.

This study explores the subjective evaluation of supplementary motor area (SMA) regulation performance in a real-time functional magnetic resonance imaging neurofeedback (fMRI-NF) task. In fMRI-NF, people learn how to self-regulate their brain activity by performing mental actions to achieve a certain target level (TL) of blood-oxygen-level-dependent (BOLD) activation. Here, we studied two types of self-evaluation: performance predictions and perceived confidence in the prediction judgement.