Publications by authors named "J H Chong"

A new pneumonia detection method is proposed to provide both pneumonia detection in respiratory sound signals and wheeze and crackle discrimination when pneumonia episodes are detected. In the proposed method, two-step hierarchy, classifying pneumonia in the first step and discriminating wheezing and crackling in the second step, is considered; the conventional pneumonia detection method is modified to improve pneumonia detection performance, while wheezing and crackling discrimination functionality is added to facilitate the application of appropriate remedies for each case. We used resampling techniques to address the imbalance in the ICBHI pneumonia dataset.

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Article Synopsis
  • Accurate diagnosis of Alzheimer's disease and vascular dementia is vital for timely treatment and better patient outcomes; this study focused on plasma and retinal biomarkers for differentiation among cognitive impairment groups.
  • The study involved 509 participants aged 50 and older, categorized into groups based on cognitive function using clinical assessments, neuropsychological tests, and MRI scans.
  • The findings revealed that both retinal layer thickness and plasma biomarker levels varied significantly across cognitive impairment levels, with decreases seen in retinal thickness and increases in plasma biomarkers from normal cognition to dementia.
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Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is a well-described condition in which approximately 80% of all cases have a genetic explanation; and among sporadic cases without a family history, the genetic bases remain unclear in approximately 30% of cases. This study aimed to identify genes associated with polycystic kidney disease (PKD) in patients with sporadic cystic kidney disease in which a clear genetic change was not identified in established genes.

Methods: A next-generation sequencing panel analyzed known genes related to kidney cysts in 118 sporadic cases, followed by whole-genome sequencing (WGS) on 47 unrelated individuals without identified candidate variants.

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A 27-year-old female with a history of acute lymphoblastic leukemia in remission presented with chest pain, liver cirrhosis, and a thrombus in the hepatic vein on ultrasound. Further workup with computed tomography (CT) and magnetic resonance imaging (MRI) revealed a mass extending from the inferior vena cava to the right atrium, 3.4 x 3.

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