Publications by authors named "J H Calvet"

Introduction: Axial spondyloarthritis (axSpA) is a chronic inflammatory condition associated with considerable pain and impaired health-related quality of life (HRQoL) for affected patients. Despite the documented increase in healthcare resource utilization (HRU) related to axSpA, few studies have explored the impact of diagnostic delays on these outcomes. This study sought to determine the association between diagnostic delay of axial spondyloarthritis (axSpA) and costs in the 3 years after diagnosis.

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Objectives: To compare mortality rates between GCA patients and the general population in Spain, and to identify associated factors influencing mortality.

Methods: ARTESER, a multicenter registry by the Spanish Society of Rheumatology, includes GCA patients from June 2013 to March 2019. Demographic, clinical, imaging, histological and mortality data were collected retrospectively.

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Background: Inflammatory bowel disease (IBD) affects 5%-10% of ankylosing spondylitis (AS) patients. Prior data suggest AS patients with IBD may have more severe disease and lower HLA-B27 prevalence. Yet, little is known about potential distinctions in AS with IBD compared to those without IBD.

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Article Synopsis
  • * Genetic studies have identified issues with Notch signaling and inflammasome function in HS, while syndromic HS is linked to mutations in certain autoinflammatory syndromes like PAPA and PASH.
  • * Research in proteomics and microbiome profiling highlights inflammatory pathways and a disturbed balance of bacteria in HS lesions, while metabolomic studies reveal imbalances in tryptophan and lipid metabolism, indicating potential bacterial involvement; however, establishing strong links across these
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