Publications by authors named "J H Bouckaert"
Monoclonal antibodies recognizing nonprotein antigens remain largely underrepresented in our understanding of the molecular repertoire of innate and adaptive immunity. One such antibody is Mannitou, a murine IgM that recognizes paucimannosidic glycans. In this work, we report the production and purification of the recombinant antigen-binding fragment (Fab) of Mannitou IgM (Mannitou Fab) and employ a combination of biochemical and biophysical approaches to obtain its initial structural characterization.
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- The article discusses the development of gold nanorods with a silica core-shell structure, which are enhanced with verteporfin, a photosensitizer used in photodynamic therapy.
- It emphasizes the high effectiveness of these nanostructures in the photodynamic inactivation of targeted cells or pathogens.
- The authors express concern regarding potential issues or limitations identified in the study, which may impact the reproducibility or applicability of the findings in clinical settings.
Article Synopsis
- The study explores a method using anti-fimbrial modified magnetic reduced graphene oxide nanoheaters to selectively target and eliminate bacteria responsible for urinary tract infections.
- Concerns are raised about the potential implications of this selective eradication approach, including its effectiveness and safety.
- The paper emphasizes the importance of understanding both the benefits and risks associated with such innovative treatments for infections.
Expression of concern for 'Particle-based photodynamic therapy based on indocyanine green modified plasmonic nanostructures for inactivation of a Crohn's disease-associated strain' by Roxana Jijie , , 2016, , 2598-2605, https://doi.org/10.1039/C5TB02697K.
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