Publications by authors named "J H Beckman"
Sickle cell disease (SCD) is a devastating hemolytic disease, marked by recurring bouts of painful vaso-occlusion, leading to tissue damage from ischemia/reperfusion pathophysiology. Central to this process are oxidative stress, endothelial cell activation, inflammation, and vascular dysfunction. The endothelium exhibits a pro-inflammatory, pro-coagulant, and enhanced permeability phenotype.
View Article and Find Full Text PDFPurpose: To evaluate the impact of bilateral ultrasound-guided erector spinae plane blocks (ESPBs) on pain and opioid-related outcomes in a surgical population with chronic pain.
Methods: A retrospective, observational cohort study. Clinical data were extracted from the electronic medical records of patients who underwent lumbar fusion (February 2018 - July 2020).
Racial and Socioeconomic Health Disparities in Peripheral Artery Disease.
J Am Heart Assoc
November 2024
Article Synopsis
- Peripheral artery disease (PAD) is a worsening condition causing narrowing of the arteries in the legs, leading to serious risks like heart attacks and amputations, particularly affecting marginalized racial and ethnic groups in the U.S.
- Despite advances in treatment, outcomes for PAD remain worse for Black, Hispanic, and American Indian populations compared to White individuals, highlighting significant health disparities.
- Research increasingly emphasizes the importance of social determinants of health, rather than biological factors, in understanding these disparities and suggests that improved policies and strategies could promote health equity.
Article Synopsis
- - The study investigates the risk of saphenous nerve injury in patients who underwent knee surgery with adductor canal block (ACB) as part of their pain management.
- - Among 28,196 surgeries performed, only 18 cases (0.06%) of saphenous nerve injury were reported, primarily linked to anterior cruciate ligament (ACL) reconstruction.
- - While ACB was identified as a potential cause for some injuries, most were attributed to other factors, with varying prognoses for recovery reported among affected patients.