Publications by authors named "J H B Van De Bovenkamp"
Article Synopsis
- COVID-19 highlighted the urgent need for rapid diagnostic testing, revealing the limitations of traditional RT-qPCR methods, which are complex and time-consuming.
- Loop-mediated isothermal amplification (LAMP) emerged as a faster, more flexible, and cost-effective alternative for detecting SARS-CoV-2 during the pandemic, though there was a need to scale this testing method due to increased demand.
- The TOMi corona initiative developed the SMART-LAMP system, capable of processing 40,000 samples daily with comparable sensitivity to RT-qPCR, while focusing on sustainability and improving pandemic preparedness through automated testing technologies.
Background: SARS-CoV-2 is taking a huge toll on society while influenza and RSV detection are also becoming more important. These viruses pose a high burden on health care. Rapid and accurate diagnostics for these pathogens are important for swift triage in the hospital.
View Article and Find Full Text PDFOropharyngeal (CT) infections and, especially, (NG) infections are common, but few commercial nucleic acid amplification tests (NAATs) specify extragenital samples for intended use. The test characteristics of the cobas 4800 CT/NG assay were evaluated for oropharyngeal swabs. The technical validation included analysis of the specificity, sensitivity, dynamic range, linearity, efficiency, and precision.
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