In this study, we reported in vitro probiotic assessment and complete genome sequence of Bacillus subtilis DC-11 isolated from traditionally fermented Idli Batter. The strain was evaluated for probiotic properties, biofilm formation, and antimicrobial compound production. The phenotypic safety was determined by accessing the strain's ability to produce enterotoxins, degrade mucin, and antibiotic sensitivity.
View Article and Find Full Text PDFBurn and diabetic wounds present significant challenges due to their complex nature, delayed healing, pain, and high susceptibility to bacterial infections. In this study, we developed and evaluated polyurethane (PU) nanofibers embedded with heparin-functionalized silver nanoparticles (hep-AgNPs) using an electrospinning technique. The choice to functionalize silver nanoparticles with heparin was based on heparin's established role in modulating inflammation and promoting angiogenesis.
View Article and Find Full Text PDFListeriosis is a severe disease caused by the foodborne pathogen , posing a significant risk to vulnerable populations such as the elderly, pregnant women, and newborns. While relatively uncommon, it has a high global mortality rate of 20-30%. Recent research indicates that smaller outbreaks of the more severe, invasive form of the disease occur more frequently than previously thought, despite the overall stable infection rates of over the past 10 years.
View Article and Find Full Text PDFConsumption of probiotics, which are beneficial live microorganisms, has received a lot of attention because of their potential to improve health and wellness. Robust quality control measures are necessary to ensure the safety of probiotics and maximize their health effects. This review delves into the topic of quality management in probiotics, highlighting the significance of sticking to strict guidelines from manufacture to storage to distribution.
View Article and Find Full Text PDF