Publications by authors named "J Guettler"
Background: Little is known regarding the opinions of the general population on anterior cruciate ligament (ACL) graft options.
Purpose: To evaluate the general population's perception of the use of allografts versus autografts in ACL reconstruction using a previously validated online marketplace platform.
Methods: A prospective 34-question survey was distributed via the online marketplace.
Article Synopsis
- Low molecular weight heparins (LMWH) are used in pregnancy to prevent or treat thromboembolic events and may have protective effects against preeclampsia, although their use in this context is debated.
- Recent research shows that LMWH can reduce pregnancy loss and inflammation-related activation of the NLRP3 inflammasome in trophoblasts, which are crucial for a healthy pregnancy.
- The mechanism involves LMWH activating the heparin-binding epidermal growth factor (HBEGF) pathway, which prevents inflammasome activation and could provide a rationale for using LMWH in managing preeclampsia.
The purpose of this study is to compare failure rates among different techniques of primary anterior cruciate ligament (ACL) repair for the treatment of proximal ACL ruptures. Meta-analysis and systematic review were completed, and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Studies from Embase, Cochrane, and PubMed published between June 2011 and June 2022 reporting outcomes of primary ACL repair on proximal tears with a minimum two-year follow-up were included.
View Article and Find Full Text PDFThe study of very early human placentation is largely limited due to ethical restrictions on the use of embryonic tissue and the fact that the placental anatomy of common laboratory animal models varies considerably from that of humans. In recent years several promising models, including trophoblast stem cell-derived organoids, have been developed that have also proven useful for the study of important trophoblast differentiation processes. However, the consideration of maternal blood flow in trophoblast invasion models currently appears to be limited to animal models.
View Article and Find Full Text PDFThe orientation of nonspherical particles in the atmosphere, such as volcanic ash and ice crystals, influences their residence times and the radiative properties of the atmosphere. Here, we demonstrate experimentally that the orientation of heavy submillimeter spheroids settling in still air exhibits decaying oscillations, whereas it relaxes monotonically in liquids. Theoretical analysis shows that these oscillations are due to particle inertia, caused by the large particle-fluid mass-density ratio.
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