Publications by authors named "J Gregor Fetterman"

Physiology education is at the core of biomedical science and medicine. Physiology unites multiple disciplines to explain the mechanisms whereby a risk factor is associated with disease. Race, ethnicity, sexual orientation, and gender identity are associated with risk of cardiovascular disease (CVD).

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Introduction: Swisher Sweets, a leading brand of little cigars and cigarillos in the United States, switched its Twitter account to protected status, limiting access to its tweets. This study examines how the protected status of Swisher Sweets tweets influences post engagement, aiming to inform regulatory strategies for branded tobacco promotions on social media.

Method: Using natural language processing, we predicted the demographics of individuals replying to Swisher Sweets' public and protected tweets.

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Article Synopsis
  • Smokeless oral nicotine products are addictive and can negatively impact cardiovascular health, particularly in individuals with pre-existing heart or cerebrovascular conditions, and can also increase the risk of oral cancer depending on their chemical composition.
  • The market for these products has rapidly expanded since the last American Heart Association policy, particularly with the rise of tobacco-free oral nicotine pouches, but their health effects remain unstudied.
  • There is a need for strong public policies to help end tobacco addiction, focusing on preventing initiation and promoting cessation through established treatment options.
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The coordinate regulation of metabolism and epigenetics to establish cell state-specific gene expression patterns during lineage progression is a central aspect of cell differentiation, but the factors that regulate this elaborate interplay are not well-defined. The imprinted Dlk1-Dio3 noncoding RNA (ncRNA) cluster has been associated with metabolism in various progenitor cells, suggesting it functions as a regulator of metabolism and cell state. Here, we directly demonstrate that the Dlk1-Dio3 ncRNA cluster coordinates mitochondrial respiration and chromatin structure to maintain proper cell state.

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Background: Co-use of alcohol and e-cigarettes (often called vaping) has been linked with long-term health outcomes, including increased risk for substance use disorder. Co-use may have been exacerbated by the COVID-19 pandemic. Social networking sites may offer insights into current perspectives on polysubstance use.

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