Publications by authors named "J Greenhalgh"
Background: Globally, drug-related deaths (DRDs) are increasing, posing a significant challenge. Scotland has the highest DRD rate in Europe and one of the highest globally. The Scottish Government launched the Digital Lifelines Scotland (DLS) program to increase the provision of digital technology in harm reduction services and other support services.
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- Renal cell carcinoma is the most prevalent kidney cancer, representing about 85% of renal cancers, with patients categorized based on their risk for disease progression.
- The objective of the appraisal was to evaluate the effectiveness and cost-effectiveness of the drug combination lenvatinib plus pembrolizumab compared to other approved treatments such as sunitinib and nivolumab plus ipilimumab.
- The assessment relied on systematic reviews and meta-analyses, specifically analyzing data from the CLEAR trial, which supported the efficacy and safety of lenvatinib combined with pembrolizumab over sunitinib.
Aim: To explain how the clinical and organisational context influenced the way the Pressure Ulcer Risk Primary or Secondary Evaluation Tool (PURPOSE-T) is used by nursing staff to support their clinical judgement and decision making about care planning and delivery.
Methods: A realist process evaluation was undertaken in a large acute hospital trust using mixed methods incorporating organisational policy review, staff semi-structured, ethnographic observation of clinical care and patient record review. Approximately 75 h of ethnographic field work involving 72 patients, 15 patient record reviews and 16 staff interviews were undertaken on 4 wards.
Background: Deaths due to drug overdose are an international issue, causing an estimated 128,000 global deaths in 2019. Scotland has the highest rate of drug-related deaths in Europe, with those in the most deprived areas at greater risk than those in affluent areas. There is a paucity of research on digital solutions, particularly from the perspective of those who use drugs who additionally access harm reduction and homelessness support services.
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