Real-world apremilast use in biologic-naïve psoriatic arthritis patients. Data from Spanish clinical practice.

Introduction: Apremilast is approved for treatment of psoriasis and psoriatic arthritis (PsA). Real-world evidence on apremilast effectiveness in clinical practice is limited.

Methods: Observational study enrolling adult patients, across 21 Spanish centres, who had initiated apremilast in the prior 6 (±1) months and were biologic naive.

Efficacy of Tofacitinib in the Treatment of Psoriatic Arthritis: A Systematic Review.

Introduction: Therapeutic approaches for psoriatic arthritis (PsA) include non-pharmacologic therapies, symptomatic treatments, tumor necrosis factor inhibitors, interleukin inhibitors, cytotoxic T lymphocyte antigen 4 immunoglobulin, and Janus kinase inhibitors. This systematic review aimed to provide complete and up-to-date information on efficacy of tofacitinib in the treatment of PsA, giving special attention to non-skin manifestations (peripheral arthritis, axial disease, enthesitis, and dactylitis).

Methods: A search of studies published between January 2016 and June 2020 was carried out on PubMed and Google Scholar.

Atlas of axial spondyloarthritis in Spain 2017: Study design and population.

Objective: Atlas of Axial Spondyloarthritis in Spain 2017 aims to better understand the reality of the patients suffering from this disease from an integrated approach.

Methods: The Atlas 2017 based its results on an extensive cross-sectional patient survey conducted in Spain (2016), validated by a multidisciplinary group of experts on spondyloarthritis.

Results: Data from 680 patients with axSpA were obtained, most of them suffered from AS, were HLA-B27 positive, older than 45 years, and live as part of a couple.

Influence of HLA-B27 on the Ankylosing Spondylitis phenotype: results from the REGISPONSER database.

Objective: To assess HLA-B27 influence on the clinical phenotype of Ankylosing Spondylitis (AS) patients.

Method: An observational, cross-sectional and descriptive study of AS patients from the Spanish REGISPONSER database was performed. Demographic, clinical, disease activity (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP)), and radiographic data (Bath Ankylosing Spondylitis Radiology Index (BASRI) score) were compared regarding HLA-B27 status.

The Spanish Psoriasis Patients' Association According to Its Members: Cross-Sectional Descriptive Study of Members' Opinions of the Association's Functions.

Introduction: Patient associations form part of health care systems, but little is known about how their members' view the functionality of these associations and whether they endorse their goals and activities.

Objective: To study how the members of the leading Spanish association of patients with psoriasis and their relatives view the group's functioning.

Material And Methods: Survey study using a self-administered questionnaire answered by members of the association (total membership, 26 349 persons).