Publications by authors named "J Graille"

Background: HIV infection is highly prevalent in French Guiana, a territory where leprosy is also endemic. Since the introduction of Highly Active Antiretroviral Treatment (HAART) in the management of HIV, leprosy has been reported as part of the immune reconstitution inflammatory syndrome (IRIS).

Methodology/principal Findings: We aimed to present a general description of these forms of leprosy as IRIS, highlighting clinical and therapeutic specificities.

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Article Synopsis
  • * A 48-year-old woman exhibited a nail lesion and pseudo-clubbing in her right index finger; X-rays showed transverse osteolysis in the distal phalanx, while other clinical exams were normal.
  • * The case emphasizes the unique characteristics of transverse AO and its potential links to various causes, noting the significance of nail involvement in diagnosis, marking it as the first documented instance of transverse AO in a single finger linked to brachyonychia without a known cause.
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We will consider the Grignard chemical deacylation to study the regioanalysis of triacylglycerols (TAGs). Using a given TAG structure, a cross-contamination model is developed and used for evaluating the incidence of the acyl migration and its influence on the accuracy of a regiospecific analysis of the molecule. Despite unavoidable isomerization, the newly formed alpha,beta-diacylglycerols are considered as most representative of the original TAG composition.

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