Publications by authors named "J Govindaraj"

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon condition, which can result either from a primary genetic abnormality affecting children or secondary to various conditions like malignancy or infection predominantly in adults. HLH is associated with immune dysregulation, resulting in an uncontrolled overproduction and infiltration of lymphocytes and histiocytes. The infiltration predominantly involves liver, spleen, lymph nodes, and central nervous system.

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The turmeric plant was used in ancient medicine to cure a wide range of diseases, including cough, diabetes, and liver disease. Data shows that the principal chemical component of turmeric, curcumin, has a variety of beneficial effects on the body. Therefore, it is of interest to document data on the therapeutic activities of turmeric, including its extracts and possible medical uses, as well as its oral and dental uses and a safety assessment of those uses.

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Neuro-osteoarthropathy often called as Charcot joint results from decreased sensory innervations of the involved joint resulting in severely damaged and disrupted joints and involvement of adjacent soft tissues. Charcot joint is characterized by the "6Ds," which are i) distended joints, ii) density increase, iii) debris production, iv) dislocation, v) disorganization, and vi) destruction. Hip joint involvement is very rare probably because of rich nerve supply compared with other peripheral joints.

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Rabies is a major disease burden worldwide, especially in Asia. Approximately, 59,000 human deaths per year occurs in over 150 countries due to rabies, with Africa and Asia contributing 95% of cases. It is a fatal infection of central nervous system (CNS) caused by rabies RNA virus via transmission through bite of an infected animal, aerosols, open wound, or organ transplantation.

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Detection of marrow infiltration is crucial in extramedullary B cell non-Hodgkin lymphoma (B-NHL). We studied the efficiency of high acquisition flow cytometry (FCM) in detecting marrow involvement in B-NHL patients and compared its performance with marrow aspiration (BMA) cytology, marrow biopsy (BMB), and positron emission tomography (PET). No case with marrow infiltration was found to be BMB positive and FCM negative.

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