Publications by authors named "J Gottswinter"

The incidence of palpable goiters, the thyroid functional state and thyroid radioisotope uptake was analyzed retrospectively in 80 patients with acromegaly and 80 patients with prolactinomas. 71% of all patients with acromegaly had an enlargement of the thyroid (goiter); 49% of them had diffuse and 39% nodular goiters. The incidence of goiters in patients with prolactinomas from the same iodine deficient geographic region was only 35% (82% diffuse and 18% nodular).

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Parathyroid carcinoma, as a malignant tumour of an endocrine gland, is a rare entity. This causes difficulties in the diagnosis as well in the therapeutic approach. Some clinical courses of this malignant disease are demonstrated.

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Three patients with a sporadic form of multiple endocrine neoplasia (MEN) IIb are presented. MEN IIb is the association of medullary carcinoma of the thyroid (MTC), pheochromocytoma and multiple mucosal neuromata. The age at diagnosis and primary therapy of MTC was relatively late (8, 16, 18 years) although thyroid enlargement (two cases), typical marfanoid habitus (two cases) or multiple mucosal neuromata (one case) had been evident since early childhood.

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Article Synopsis
  • Two men aged 48 and 54 experienced gynecomastia and loss of potency after using hair lotions containing estrogen.
  • Increased levels of 17-beta estradiol were observed alongside decreased testosterone and gonadotropin levels during lotion use.
  • The use of estrogen-containing hair products should be considered in diagnosing gynecomastia in similar cases.
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The parathyroid carcinoma is a rare cause of primary hyperparathyroidism. It deserves special attention in regard to diagnosis and treatment. Within a period of 10 years we observed 117 patients with primary hyperparathyroidism (pHPT) at the University Hospitals of Ulm and Heidelberg.

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