Publications by authors named "J Gonzalez-Gutierrez"
The hydration shell of a protein is so important and an integral part of it, that protein's structure, stability and functionality cannot be conceived in its absence. This layer has unique properties not found in bulk water. However, ions, always present in the protein environment, disturb the hydration shell depending on their nature and concentration.
View Article and Find Full Text PDFIntroduction: Measuring social value has always been a challenge for organizations that generate such value, including foundations, NGOs, social enterprises, and governmental entities. Often, the benefits of these initiatives are perceived as intangible or long-term, making them difficult to quantify. Assessing social value demonstrates the impact of investments and accountability to stakeholders.
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- Myval technology is a new balloon-expandable option for treating heart valve issues, emerging after the established Edwards system, and its usage is increasing despite some debated points.
- A thorough literature review covering studies from December 2016 to May 2024 showed Myval to be effective for native aortic stenosis with low mortality and complication rates, and its performance compares favorably to other devices.
- The findings also indicate that Myval is safe for various off-label uses, achieving high success rates across different heart valve procedures, although more extensive studies are needed to confirm these results.
Article Synopsis
- User-friendly assessment tools for malnutrition are essential, and this study focused on a personalized nutrition intervention using a new oral nutritional supplement and AI technology to track outcomes in malnourished patients.
- The study included 65 patients and showed significant improvements over three months, with weight loss decreasing, and a drop in the prevalence of malnutrition and severe malnutrition.
- Additionally, older patients experienced gains in muscle thickness, strength, and function, indicating that tailored interventions can effectively enhance nutrition and combat malnutrition in patients with disease-related issues.
Article Synopsis
- The study evaluated the effectiveness of the Vasopressor test (VPT) in patients with functional mitral regurgitation (MR) and left ventricular dysfunction undergoing transcatheter edge-to-edge repair (TEER).* -
- Out of 1115 patients, those who underwent VPT had higher rates of significant MR and greater overall mortality at one year compared to those who did not undergo the test, indicating a potentially higher risk profile.* -
- Despite the increased mortality rates in the VPT group, other key outcomes like heart failure readmissions and cardiovascular mortality showed no significant differences, suggesting VPT can aid in managing high-risk patients without worsening long-term outcomes.*