Publications by authors named "J Golding"

Article Synopsis
  • The study examined how ischemia, retinal fluid, and layer thickness impact visual acuity (VA) in patients with retinal vein occlusion (RVO) using swept-source optical coherence tomography (OCT).
  • Patients received aflibercept injections and were monitored through OCT analysis at baseline and after 3 and 6 months, correlating OCT findings with changes in best-corrected VA (BCVA).
  • Results showed that a combination of intraretinal fluid (IRF) volume, thickness measurements in specific retinal layers, and ischemic indices had the strongest correlation with changes in VA, highlighting useful clinical markers for RVO management.
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Previous research on child/teenage sexual experiences has largely focussed on negative outcomes such as teen pregnancy or acquiring sexually transmitted infections and are mainly cross-sectional. Longitudinal research is required to assess normal sexual development and the attainment of psychologically healthy attitudes towards sexuality. The Avon Longitudinal Study of Parents and Children (ALSPAC) has administered questions on relationships and sexual experiences from the age of 11 years to the index children.

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The long non-coding RNA (lncRNA), HAR1A is emerging as a putative tumour suppressor. In non-neoplastic brain cells, REST suppresses HAR1A expression. In gliomas REST acts as an oncogene and is a potential therapeutic target.

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Article Synopsis
  • This data note focuses on the sexual experiences and behaviors of parents from the Avon Longitudinal Study of Parents and Children (ALSPAC), which began with 14,541 pregnant women in southwest England during the early 1990s.
  • It highlights the collection of data regarding childhood sexual experiences, sexual abuse, and adult sexual assault, as well as parental satisfaction in relationships and sexual orientations.
  • The study aims to explore generational differences in sexual behaviors between parents and their children, allowing for comparisons with other similar longitudinal surveys like NATSAL-3.
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To assess the differences in morphological photoreceptor outcomes measured using adaptive optics (AO)-assisted imaging between individuals with diabetes or prediabetes and healthy controls. A systematic search was conducted across MEDLINE, Embase, and Cochrane databases from January 2000 to June 2023. Studies that used AO-assisted imaging modalities to quantitatively compare photoreceptor outcomes in patients with diabetes or prediabetes with healthy controls were included.

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