High frequency of neurosyphilis in HIV-positive patients diagnosed with early syphilis.

Background: Syphilis is an infection frequently seen with HIV, and European guidelines on the management of syphilis suggest that HIV-infected patients may have an increased risk of early neurological involvement, sometimes asymptomatic. Recent study shows a relationship between neurosyphilis and cerebrospinal fluid (CSF) HIV viral load (VL), which in turn may be associated with subsequent neurocognitive decline.

Objectives And Methods: The aim of the study was estimation of the frequency of neurosyphilis among HIV-positive patients with early syphilis.