Publications by authors named "J Giovannoni"
Gene expression profiling is of key importance in all domains of life sciences, as medicine, environment, and plants, for both basic and applied research. Despite the emergence of microarrays and high-throughput sequencing, qPCR remains a standard method for gene expression analyses, with its data normalization step being crucial for ensuring accuracy. Currently, the most widely used normalization method is based on the use of reference genes, assumed to be stably expressed across all experimental conditions.
View Article and Find Full Text PDFThe gut microbiome of worms from composting facilities potentially harbors organisms that are beneficial to plant growth and development. In this experiment, we sought to examine the potential impacts of rhizosphere microbiomes derived from Eisenia fetida worm castings (i.e.
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- Early harvesting of fruits, like tomatoes, interrupts their normal development, affecting quality, though they can still ripen postharvest.
- Even tomatoes picked extremely early can mature and the seeds remain viable, developing into healthy plants.
- A key factor influencing cuticle defects in these early-harvested tomatoes was identified, suggesting that the processes for later maturation begin early and are not reliant solely on complete growth or being attached to the plant.
The ARID1A and ARID1B subunits are mutually exclusive components of the BAF variant of SWI/SNF chromatin remodeling complexes. Loss of function mutations in ARID1A are frequently observed in various cancers, resulting in a dependency on the paralog ARID1B for cancer cell proliferation. However, ARID1B has never been targeted directly, and the high degree of sequence similarity to ARID1A poses a challenge for the development of selective binders.
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