Publications by authors named "J Gimnig"
Background: In Myanmar, progress towards malaria elimination has stagnated in some areas requiring deployment of new tools and approaches to accelerate malaria elimination. While there is evidence that networks of community-based malaria workers and insecticide-treated nets (ITNs) can reduce malaria transmission in a variety of settings, evidence for the effectiveness of other interventions, such as topical repellents, is limited. Since malaria transmission in Myanmar occurs outdoors, mainly among forest-goers, this study tested the effectiveness of topical repellents in combination with supplemental ITN distribution and strengthened networks of malaria workers.
View Article and Find Full Text PDFBackground: Spatial repellent products are used for prevention of insect bites, and a body of evidence exists on spatial repellent entomological efficacy. A new option for vector control, spatial repellent products are designed to release active ingredient into the air for disruption of human-vector contact thereby reducing human exposure to mosquito-borne pathogens. Clinical trials have shown spatial repellent epidemiological efficacy against Aedes-borne viruses but inconclusive outcomes against malaria.
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- Pyrethroid-chlorfenapyr nets, like PermaNet Dual, show better effectiveness against pyrethroid-resistant Anopheles funestus compared to traditional nets in Kenya.
- The study used a rigorous experimental hut trial with a Latin Square design to compare PermaNet Dual and Interceptor G2 in terms of mosquito mortality and blood feeding rates.
- Results indicated that PermaNet Dual was non-inferior to Interceptor G2 for mosquito mortality but had a lower effectiveness in preventing blood feeding compared to PermaNet 3.0, suggesting its potential for use in malaria vector control.
Article Synopsis
- The study evaluates various mosquito sampling methods, including UV light traps, CDC light traps, and Prokopack aspiration, against the traditional human landing catches (HLC) in Kenya to address safety and efficacy.
- Out of 5,370 Anopheles mosquitoes collected, the majority were An. funestus sensu lato, with a notable infection prevalence of 3.1% found only in this species.
- Indoor aspiration proved to be the most effective method for capturing An. funestus compared to light traps, while UV light traps significantly outperformed HLC outdoors for collecting various Anopheles species.
Background: Insecticide-treated nets (ITNs) contributed significantly to the decline in malaria since 2000. Their protective efficacy depends not only on access, use, and net integrity, but also location of people within the home environment and mosquito biting profiles. Anopheline mosquito biting and human location data were integrated to identify potential gaps in protection and better understand malaria transmission dynamics in Busia County, western Kenya.
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