Publications by authors named "J Ghika"

Objectives: Tardive dystonia/dyskinesia (TDD) occurs as a side effect of anti-dopaminergic drugs, including metoclopramide, and is often refractory to medication. While pallidal deep brain stimulation (DBS) has become an accepted treatment for TDD secondary to neuroleptic medication, there is much less knowledge about its effects on metoclopramide-induced TDD.

Methods: We present the case of a woman with metoclopramide-induced TDD, whose symptoms were initially misjudged as "functional.

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Objective: Sinusitis or rhinosinusitis is a very common disease worldwide, and in some cases, it leads to intracranial complications (ICS). These are more common in immunocompromised patients or with underlying comorbidities, but even healthy individuals, can be affected. Nowadays, ICS have become less common thanks to improved antibiotic therapies, radiological diagnostic methods, surgical techniques and skills.

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Hallucinations in Parkinson's disease (PD) are disturbing and frequent non-motor symptoms and constitute a major risk factor for psychosis and dementia. We report a robotics-based approach applying conflicting sensorimotor stimulation, enabling the induction of presence hallucinations (PHs) and the characterization of a subgroup of patients with PD with enhanced sensitivity for conflicting sensorimotor stimulation and robot-induced PH. We next identify the fronto-temporal network of PH by combining MR-compatible robotics (and sensorimotor stimulation in healthy participants) and lesion network mapping (neurological patients without PD).

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Article Synopsis
  • The study explores the impact of non-drug interventions (NDIs) on the quality of life (QOL) for patients with age-related neurodegenerative diseases and their caregivers, revealing no significant difference in QOL between single and multiple NDIs.
  • Socio-demographic factors, such as age, gender, and caregivers' occupational status, significantly influenced the QOL of both patients and caregivers throughout the study.
  • The findings suggest that maintaining consistent NDIs over time is crucial for preserving the QOL of patients and reducing caregivers' anxiety and depression.
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