Publications by authors named "J Ghelfi"
Article Synopsis
- Pathogenic variants in the LRRK2 gene significantly contribute to Parkinson's disease, but not everyone with these variants develops the disease, suggesting lifestyle and environmental factors play a role.
- A study analyzed household dust samples from different groups, including patients with and without PD and a healthy control group, identifying over 1,000 chemicals and 163 types of microorganisms, with some shown to be statistically significant in relation to PD.
- Notably, hazardous chemicals like Bisphenol S were linked to negative effects on mitochondrial function in nerve cells from PD patients, highlighting the potential impact of environmental exposures on Parkinson's disease development.
Article Synopsis
- This study investigates the effectiveness of uterine artery embolization (UAE) with gelatin foam to manage delayed bleeding caused by vascularized retained products of conception (vRPOC) after abortion or miscarriage during a 5-year period at 11 French hospitals.
- Out of 224 patients evaluated, 94.2% experienced clinical success, although 7.3% showed persistent vRPOC at imaging follow-ups, with some minor and major complications reported.
- The results suggest that while UAE with gelatin foam is generally safe and effective, certain factors like having a hypertrophic uterine artery and using gelatin foam torpedoes may increase the risk of persistent bleeding issues.