Publications by authors named "J Geraghty"

Article Synopsis
  • - Whipple disease (WD) is a rare infectious disorder that primarily affects the gastrointestinal system and can also impact the central nervous system, leading to symptoms like personality changes and progressive dementia.
  • - A case study presented a 46-year-old male who initially had joint issues but developed severe cognitive decline over five years, with MRI and lumbar puncture findings supporting the diagnosis of primary CNS-WD.
  • - The case emphasizes the need for awareness of WD in patients with unusual neurological symptoms, as early detection and treatment are vital to preventing serious health complications.
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Introduction: Despite the benefits of quitting smoking for those who have cancer, including improved health outcomes and reduced therapeutic toxicities, it is unclear how many people are supported in quit attempts during this time. Variations in the availability and provision of smoking cessation (SC) services are reported, with little understanding of the challenges and solutions. This co-designed study aimed to understand the perspectives of health care professionals (HCPs) working in oncology settings to engage in SC practices and identify recommendations for developing an SC pathway.

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The mechanism by which subarachnoid hemorrhage (SAH) leads to chronic neurologic deficits is unclear. One possibility is that blood activates microglia to drive inflammation that leads to synaptic loss and impaired brain function. Using the endovascular perforation model of SAH in rats, we investigated short-term effects on microglia together with long-term effects on EEG and neurologic function for up to 3 months.

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