Publications by authors named "J Gazzola"
The development of three-dimensional (3D) biomaterials that mimic natural tissues is required for efficiently restoring physiological functions of injured tissues and organs. In the field of soft hydrogels, self-assembled peptides (SAPs) stand out as distinctive biomimetic scaffolds, offering tunable properties. They have garnered significant attention in nanomedicine due to their innate ability to self-assemble, resulting in the creation of fibrous nanostructures that closely mimic the microenvironment of the extracellular matrix (ECM).
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- Biomaterials for tissue engineering need to resemble the native extracellular matrix in both structure and mechanical properties for effective implantation therapies.
- Self-assembling peptides (SAPs) are promising materials but often produce soft hydrogels unsuitable for tougher tissues; chemical cross-linking is a common solution but can involve toxic or expensive agents.
- The study introduces a novel, green method using microwave irradiation to enhance the stiffness and resilience of SAPs without compromising their biomimetic properties, suggesting a feasible approach for broader use in research and clinical applications.
Loss of functional capacity in elderly individuals with Alzheimer disease.
Dement Neuropsychol
December 2020
Background: The functional capacity of elderly individuals with Alzheimer disease (AD) progressively declines.
Objective: To verify the influence of sociodemographic, clinical, staging, mobility, and postural and cognitive balance data on the impairment of the functional capacity of elderly individuals with AD.
Methods: This observational, analytical, cross-sectional study was performed at the Physiotherapy Department of the Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Introduction: There is a lack of scientific studies on the assessment of patients with vestibular disorders associated with sleep quality disorders and its impact on the balance and overall quality of life.
Objectives: to assess the impact of the sleep quality on the balance and quality of life of individuals with peripheral vestibulopathies.
Methods: 52 individuals with peripheral vestibulopathies underwent sleep quality assessment through the Pittsburgh sleep quality index, neurotological examination through dizziness handicap inventory and Tetrax posturography (Sunlight Medical Ltd.
Introduction: Postural instability is one the most common disabling features in vestibular disorders.
Objective: This study aimed to analyze the limit of stability and the influence of manipulation of visual, somatosensorial and visual-vestibular information on postural control in older adults with vestibular disorder, with and without a history of falls.
Methods: Cross-sectional study.