Pathogenic are spirochetes that cause leptospirosis, a worldwide zoonotic disease. Leptospirosis affects humans and animals, with approximately 1 million human infections and 60,000 deaths per year. The diversity of leptospiral strains and serovars allied to the fact that pathogenesis is not yet fully understood, make the development of an effective vaccine against leptospirosis a challenge.
View Article and Find Full Text PDFBackground/objectives: Autism spectrum disorder (ASD) is associated with several coexisting diseases or comorbidities, including inflammatory and metabolic disorders. In fact, ASD symptoms may be associated with immune system dysfunction. However, studies investigating the peripheral blood levels of immune cells are lacking and have provided mixed findings.
View Article and Find Full Text PDFObjective: The current study investigated the factors that predict drowsy drivers' decisions regarding whether to take breaks versus continue driving during long simulator drives.
Background: Driver drowsiness contributes to substantial numbers of motor vehicle crashes, injuries, and deaths. Previous research has shown that taking a nap and consuming caffeine can temporarily mitigate drowsiness and enable continued safe driving.
Clin Implant Dent Relat Res
February 2025
Osseodensification is a novel approach that has significantly advanced the field of implant dentistry, particularly in the context of transcrestal maxillary sinus floor elevation. This technique involves the use of specially designed burs that compact and densify bone along the osteotomy walls, thereby enhancing implant primary stability and facilitating osseointegration in low-density bone. This article reviews the historical evolution of implant site preparation, and the biomechanical, histological, and clinical evidence of osseodensification with a special focus on its application in sinus floor augmentation.
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